Spinal111Indium-DTPA CSF flow studies in leptomeningeal metastasis
Identifieur interne : 000088 ( Main/Exploration ); précédent : 000087; suivant : 000089Spinal111Indium-DTPA CSF flow studies in leptomeningeal metastasis
Auteurs : RBID : ISTEX:11060_1995_Article_BF01057757.pdfEnglish descriptors
Abstract
Sixteen consecutive patients (8 men; 8 women; age range 6–63 years, median 40 years) with leptomeningeal metastasis were found by radionuclide ventriculography to have cerebrospinal fluid (CSF) flow interruption at the following sites: cisterna magna/basal cisterns (6); cervical (5) and thoracic (3) spinal subarachnoid space. Two additional patients had no evidence of interruption of CSF flow. All patients underwent intralumbar injection of111Indium-DTPA and imaging of spinal ascent of radionuclide, corroborating sites of CSF flow disruption seen by radionuclide ventricuiography. Median (range) time to appearance in lumbar, thoracic and cervical spinal subarachnoid compartments were 1 (1), 22.5 (20–25) and 32.5 (30–35) minutes respectively. Appearance of radionuclide in the cisterna magna/basal cisterns, sylvian cisterns, ventricular system and high cerebral convexity was 37.5 (35–40), 65 (60–70), 1440 (1440) and 1440 (1440) minutes respectively. Only 1 of 8 patients with interruption of CSF flow within the spinal subarachnoid space shown by intralumbar radionuclide flow study, was seen by either CT myelography or contrast enhanced spine MR to have CSF flow block. No patient with base of brain block (0/6) shown by radionuclide CSF flow studies demonstrated CSF flow disruption by either cranial contrast enhanced CT or MR. In conclusion, spinal111In-DTPA CSF flow studies confirmed sites of CSF flow block shown by radionuclide ventriculography and demonstrate the feasibility of assessing CSF compartmentalization by intralumbar radionuclide administration. Furthermore, radionuclide CSF flow studies when compared to conventional neuroradiographic imaging are more sensitive in demonstrating interruption of CSF flow.
DOI: 10.1007/BF01057757
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title>Spinal111Indium-DTPA CSF flow studies in leptomeningeal metastasis</title><author><name>Marc C. Chamberlain</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurosciences, University of California, San Diego, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurosciences, University of California, San Diego</wicri:regionArea><wicri:noRegion>San Diego</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="RBID">ISTEX:11060_1995_Article_BF01057757.pdf</idno><date when="1995">1995</date><idno type="doi">10.1007/BF01057757</idno><idno type="wicri:Area/Main/Corpus">000A48</idno><idno type="wicri:Area/Main/Curation">000A48</idno><idno type="wicri:Area/Main/Exploration">000088</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Leptomeningeal metastasis</term><term>Spinal CSF flow studies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="eng">Sixteen consecutive patients (8 men; 8 women; age range 6–63 years, median 40 years) with leptomeningeal metastasis were found by radionuclide ventriculography to have cerebrospinal fluid (CSF) flow interruption at the following sites: cisterna magna/basal cisterns (6); cervical (5) and thoracic (3) spinal subarachnoid space. Two additional patients had no evidence of interruption of CSF flow. All patients underwent intralumbar injection of111Indium-DTPA and imaging of spinal ascent of radionuclide, corroborating sites of CSF flow disruption seen by radionuclide ventricuiography. Median (range) time to appearance in lumbar, thoracic and cervical spinal subarachnoid compartments were 1 (1), 22.5 (20–25) and 32.5 (30–35) minutes respectively. Appearance of radionuclide in the cisterna magna/basal cisterns, sylvian cisterns, ventricular system and high cerebral convexity was 37.5 (35–40), 65 (60–70), 1440 (1440) and 1440 (1440) minutes respectively. Only 1 of 8 patients with interruption of CSF flow within the spinal subarachnoid space shown by intralumbar radionuclide flow study, was seen by either CT myelography or contrast enhanced spine MR to have CSF flow block. No patient with base of brain block (0/6) shown by radionuclide CSF flow studies demonstrated CSF flow disruption by either cranial contrast enhanced CT or MR. In conclusion, spinal111In-DTPA CSF flow studies confirmed sites of CSF flow block shown by radionuclide ventriculography and demonstrate the feasibility of assessing CSF compartmentalization by intralumbar radionuclide administration. Furthermore, radionuclide CSF flow studies when compared to conventional neuroradiographic imaging are more sensitive in demonstrating interruption of CSF flow.</div></front></TEI><mods xsi:schemaLocation="http://www.loc.gov/mods/v3 file:///applis/istex/home/loadistex/home/etc/xsd/mods.xsd" version="3.4" istexId="b89be965ce6acf1fe96e42386e6bc8fcc538e456"><titleInfo lang="eng"><title>Spinal111Indium-DTPA CSF flow studies in leptomeningeal metastasis</title></titleInfo><name type="personal"><namePart type="given">Marc C.</namePart><namePart type="family">Chamberlain</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Neurosciences, University of California, San Diego, USA</affiliation></name><typeOfResource>text</typeOfResource><genre>Original Paper</genre><originInfo><publisher>Kluwer Academic Publishers, Dordrecht</publisher><dateValid encoding="w3cdtf">2005-01-12</dateValid><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="eng">Sixteen consecutive patients (8 men; 8 women; age range 6–63 years, median 40 years) with leptomeningeal metastasis were found by radionuclide ventriculography to have cerebrospinal fluid (CSF) flow interruption at the following sites: cisterna magna/basal cisterns (6); cervical (5) and thoracic (3) spinal subarachnoid space. Two additional patients had no evidence of interruption of CSF flow. All patients underwent intralumbar injection of111Indium-DTPA and imaging of spinal ascent of radionuclide, corroborating sites of CSF flow disruption seen by radionuclide ventricuiography. Median (range) time to appearance in lumbar, thoracic and cervical spinal subarachnoid compartments were 1 (1), 22.5 (20–25) and 32.5 (30–35) minutes respectively. Appearance of radionuclide in the cisterna magna/basal cisterns, sylvian cisterns, ventricular system and high cerebral convexity was 37.5 (35–40), 65 (60–70), 1440 (1440) and 1440 (1440) minutes respectively. Only 1 of 8 patients with interruption of CSF flow within the spinal subarachnoid space shown by intralumbar radionuclide flow study, was seen by either CT myelography or contrast enhanced spine MR to have CSF flow block. No patient with base of brain block (0/6) shown by radionuclide CSF flow studies demonstrated CSF flow disruption by either cranial contrast enhanced CT or MR. In conclusion, spinal111In-DTPA CSF flow studies confirmed sites of CSF flow block shown by radionuclide ventriculography and demonstrate the feasibility of assessing CSF compartmentalization by intralumbar radionuclide administration. Furthermore, radionuclide CSF flow studies when compared to conventional neuroradiographic imaging are more sensitive in demonstrating interruption of CSF flow.</abstract><subject lang="eng"><genre>Key words</genre><topic>spinal CSF flow studies</topic><topic>leptomeningeal metastasis</topic></subject><relatedItem type="series"><titleInfo type="abbreviated"><title>J Neuro-Oncol</title></titleInfo><titleInfo><title>Journal of Neuro-Oncology</title><partNumber>Year: 1995</partNumber><partNumber>Volume: 25</partNumber><partNumber>Number: 2</partNumber></titleInfo><genre>Archive Journal</genre><originInfo><dateIssued encoding="w3cdtf">1995-06-01</dateIssued><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><subject usage="primary"><topic>Medicine & Public Health</topic><topic>Oncology</topic></subject><identifier type="issn">0167-594X</identifier><identifier type="issn">Electronic: 1573-7373</identifier><identifier type="matrixNumber">11060</identifier><identifier type="local">IssueArticleCount: 10</identifier><recordInfo><recordOrigin>Kluwer Academic Publishers, 1995</recordOrigin></recordInfo></relatedItem><identifier type="doi">10.1007/BF01057757</identifier><identifier type="matrixNumber">Art6</identifier><identifier type="local">BF01057757</identifier><accessCondition type="use and reproduction">MetadataGrant: OpenAccess</accessCondition><accessCondition type="use and reproduction">AbstractGrant: OpenAccess</accessCondition><accessCondition type="restriction on access">BodyPDFGrant: Restricted</accessCondition><accessCondition type="restriction on access">BodyHTMLGrant: Restricted</accessCondition><accessCondition type="restriction on access">BibliographyGrant: Restricted</accessCondition><accessCondition type="restriction on access">ESMGrant: Restricted</accessCondition><part><extent unit="pages"><start>135</start><end>141</end></extent></part><recordInfo><recordOrigin>Kluwer Academic Publishers, 1995</recordOrigin><recordIdentifier>11060_1995_Article_BF01057757.pdf</recordIdentifier></recordInfo></mods></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=IndiumV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000088 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000088 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= *** parameter Area/wikiCode missing ***
|area= IndiumV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:11060_1995_Article_BF01057757.pdf
|texte= Spinal111Indium-DTPA CSF flow studies in leptomeningeal metastasis
}}
| This area was generated with Dilib version V0.5.81. |  |